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How quickly does inhaler work? It works by relaxing the muscles of the airways into the lungs, which makes it easier to breathe. When you take a puff of your salbutamol inhaler it works almost straight away to make your breathing easier. It carries on working for about 5 hours.
How long does an asthma inhaler stay in your system? How long do they stay in your system ? Most inhaled steroids have a beneficial effect for 12 hours. The exceptions are Arnuity Ellipta, Asmanex, and Trelegy Ellipa, which last for 24 hours.
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